The Impact of Stress on the Nervous System: An Overview 

Discover how chronic stress impacts our nervous system, leading to health issues. Learn effective stress management techniques to restore balance.
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Stress is like a storm, quietly influencing our nervous system 12 and potentially altering our health. Chronic stress impacts our body’s control center, not just making us feel uneasy or nervous. It can bring about health issues later on. This article will explain how stress affects our nervous system and offer ways to combat its impact. 

Key Takeaways 

  • Chronic stress alters the nervous system, affecting health; stress management is essential for well-being. 
  • Balance in the autonomic nervous system is crucial for stress management and maintaining health. 
  • An overactive amygdala causes continuous stress and anxiety, impacting mental health and nervous system balance. 
  • Neurotransmitter imbalances indicate a dysregulated nervous system, often resulting from prolonged stress exposure. 
  • Effective stress management includes mindfulness, exercise, a balanced diet, cognitive therapy, and quality sleep. 

This blog is part of a series on “what is stress?“. The next blog is about the power of the vagus nerve.

Understanding the Autonomic Nervous System 

Let’s delve into the complexities of the autonomic nervous system, the body’s automatic control center for heart rate, digestion, and breathing. This system is divided into two primary parts: the sympathetic and parasympathetic nervous systems. 

The sympathetic nervous system is our body’s ‘fight or flight’ response. It’s what accelerates our heart rate, increases our blood pressure, and prepares us for action. Conversely, the parasympathetic nervous system is often referred to as the ‘rest and digest’ system. It’s what slows our heart rate, lowers our blood pressure, and helps our bodies conserve energy. 

When we talk about parasympathetic vs sympathetic, it’s essentially a balance between these two systems that keeps us healthy. If we’re constantly in ‘fight or flight’ mode, it can lead to chronic stress and health issues. That’s where activating the parasympathetic nervous system comes in. It can be as simple as deep breathing or meditation to help us relax and restore balance. 

The Brain’s Alarm System 

Understanding how our bodies respond to stress involves more than just the sympathetic and parasympathetic systems; we also need to consider the brain’s alarm system. This alarm system is primarily controlled by a small, almond-shaped part of the brain called the amygdala. The amygdala’s function is to alert us to potential threats, triggering the stress nervous system to prepare us to respond. 

However, when the amygdala becomes overactive, it can lead to constant stress and anxiety. This is often referred to as an ‘amygdala hijack’, where the brain’s alarm system overreacts to non-threatening situations. For instance, amygdala hijack examples can range from getting excessively angry in a traffic jam to panicking over a minor work issue. 

Symptoms of brain stress can manifest in various ways, including loss of focus, memory problems, and even physical symptoms like headaches. These are clear signs that the brain’s alarm system is working overtime and needs to be calmed. 

Neurotransmitters and their Role in Stress Regulation 

Diving into the role of neurotransmitters, these chemical messengers play a pivotal part in stress regulation. They’re integral in the classification of neurotransmitters and can reveal signs of a dysregulated nervous system. 

Neurotransmitter Function Impact of Stress 
Dopamine Regulates mood and pleasure Excess can lead to nervous system fatigue symptoms 
Serotonin Controls mood, appetite, and sleep Shortage can result in cns fatigue symptoms 
Norepinephrine Responds to stress Overproduction can cause overactive amygdala symptoms 
The Role of Neurotransmitters

When there’s an imbalance of these neurotransmitters, we’ll likely see signs of a dysregulated nervous system, such as nervous system fatigue symptoms or CNS fatigue symptoms. These could manifest as chronic fatigue, mood swings, or anxiety, indicating stress-related issues. 

An overactive amygdala, due to excess norepinephrine, can ramp up anxiety and fear responses, further exacerbating stress. We must remember that appropriate regulation and balance of these neurotransmitters is crucial for healthy stress response, to prevent stress overload and potential burnout. 

Techniques for Regulating the Stress Response 

To manage the stress response effectively and maintain a balanced nervous system, we must explore various techniques for stress regulation. Let’s investigate how to heal a dysregulated nervous system and how to reset your nervous system. 

Firstly, mindfulness practices like meditation or yoga can be instrumental in resetting your nervous system. They help in fostering a sense of calm and tranquility, mitigating the adverse effects of stress. Moreover, a balanced diet and regular physical activity also contribute to nervous system healing. 

For those dealing with an overactive amygdala, treatment can involve cognitive-behavioral therapies, deep-breathing exercises, and exposure therapies. These interventions work by gradually reducing fear responses and enhancing the body’s resilience to stress. 

Lastly, remember that good quality sleep is crucial for regulating the stress response. It allows the nervous system to rest, repair, and rejuvenate. 

In essence, managing stress is a holistic process, one that involves the mind, body, and lifestyle. By integrating these techniques into our daily lives, we can foster a healthier, more balanced nervous system, ready to face whatever comes our way. 

Recognizing and Addressing Nervous System Dysregulation 

How do we know when our nervous system is out of balance, and what can we do to address it? The answer lies in understanding the signs of CNS fatigue and recovery methods. 

We can recognize dysregulation by observing changes in our mood, memory, and stress responses, all of which are linked to hippocampus function. Persistent stress can cause the hippocampus to shrink, leading to memory problems and emotional instability. 

To address this, we can employ strategies such as: 

  1. Parasympathetic Stimulation: This includes deep breathing exercises, meditation, and yoga. These activities stimulate the parasympathetic nervous system, helping us relax and restore balance.
  2. Amygdala Exercises: Practices like mindfulness and cognitive-behavioral therapy can help train the amygdala, our stress response center, to respond more adaptively to stress. 
  3. Healthy Lifestyle Choices: Regular exercise, a balanced diet, and adequate sleep can support general CNS fatigue recovery. 
  4. Professional Help: If our symptoms persist, we must seek professional guidance. Therapists and doctors can provide specific treatments and advice tailored to our needs.


We’ve explored the significant effects of stress on our nervous system and discussed strategies for managing stress responses and fixing imbalances. We’re now ready to dig further into the mysteries of our neurology. Isn’t it fascinating to learn about our bodies? 

Keep reading as we continue our exploration into the intriguing world of the human nervous system. Don’t miss out on this exciting learning experience! 


  1. Nervous System: What It Is, Parts, Function & Disorders ([]
  2. Nervous system – Wikipedia[]
Alex Reijnierse
Alex Reijnierse

Alex Reijnierse is a stress management expert with over a decade of experience in helping individuals effectively manage and reduce stress. He holds a Master of Science (MSc) and has a background in high-pressure environments, which has given him firsthand experience in dealing with chronic stress.